Larissa Muldoon, Nora Stapleton and Jackie Shiels were involved as the Ireland women began their defence of the RBS Six Nations title with a win over Wales in Donnybrook on Saturday.
Muldoon started as scrum half as Ireland, thanks to two first half tries, were victors 21-3.
Muldoon and Shiels were used from the bench as the Irish Women maintained their advantange in the second half.
The first half tries came from Sene Naoupu and Sophie Spence.
The Irish Women will be back in action on Saturday next as they travel to France to take on the French, who had a big 39-0 win over Italy in their opening game.
Ireland: Niamh Briggs (UL Bohemians/Munster) (capt); Elise O'Byrne White (Old Belvedere/Leinster), Aine Donnelly (Cill Dara/Leinster), Sene Naoupu (Galwegians/Connacht), Mairead Coyne (Galwegians/Connacht); Nikki Caughey (Railway Union/Ulster), Larissa Muldoon (Skewen); Ailis Egan (Old Belvedere/Leinster), Zoe Grattage (Tralee/Munster), Ruth O'Reilly (Galwegians/Connacht), Sophie Spence (Old Belvedere/Leinster), Marie Louise Reilly (Old Belvedere/Leinster), Paula Fitzpatrick (Toulouse), Claire Molloy (Bristol), Heather O'Brien (Toulouse).
Replacements used: Nora Stapleton (Old Belvedere/Leinster) for Caughney (39-40 mins, blood sub), Cliodhna Moloney (Railway Union/Leinster) for Grattage (50), Stapleton for Caughey, Ciara Griffin (Tralee/Munster) for O'Brien (both 58), Fiona Reidy (UL Bohemians/Munster) for Egan (58-61, blood sub), Ciara Cooney (Railway Union/Leinster) for Reilly, Jackie Shiels (Richmond) for Donnelly (both 66), Lindsay Peat (Railway Union/Leinster) for O'Reilly (70), Mary Healy (Galwegians/Connacht) for Muldoon (74), Reidy for Egan (77).